A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Metastatic Colorectal Cancer (Morpheus-CRC)
Latest Information Update: 06 Jun 2025
At a glance
- Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Delolimogene mupadenorepvec (Primary) ; Etrumadenant (Primary) ; Idasanutlin (Primary) ; Isatuximab (Primary) ; Odetiglucan (Primary) ; Regorafenib (Primary) ; Selicrelumab (Primary)
- Indications Adenocarcinoma; Colorectal cancer
- Focus Adverse reactions; Therapeutic Use
- Acronyms Morpheus- CRC
- Sponsors Genentech; Roche
Most Recent Events
- 30 Apr 2025 Results(n=39) evaluating the safety and efficacy of Imprime PGG in combination with atezolizumab and bevacizumab presented at the 116th Annual Meeting of the American Association for Cancer Research.
- 01 Dec 2022 Status changed from active, no longer recruiting to discontinued.
- 02 Sep 2022 Planned End Date changed from 25 Nov 2023 to 31 Dec 2022.