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INvestigating the Lowest Threshold of Vascular bENefits From LDL Cholesterol Lowering With a PCSK9 mAb InhibiTor (Alirocumab) in Patients With Stable Cardiovascular Disease (INTENSITY-HIGH)

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Trial Profile

INvestigating the Lowest Threshold of Vascular bENefits From LDL Cholesterol Lowering With a PCSK9 mAb InhibiTor (Alirocumab) in Patients With Stable Cardiovascular Disease (INTENSITY-HIGH)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 04 Dec 2023

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At a glance

  • Drugs Alirocumab (Primary) ; Atorvastatin; Ezetimibe; Rosuvastatin; Simvastatin
  • Indications Cardiovascular disorders
  • Focus Therapeutic Use
  • Acronyms INTENSITY-HIGH
  • Most Recent Events

    • 22 Jul 2021 Planned End Date changed from 30 Nov 2020 to 30 Nov 2023.
    • 17 May 2021 Results assessing non-LDL effects of PCSK9i in stable CV disease patients who were otherwise ineligible for PCSK9i treatment, presented at the 70th Annual Scientific Session of the American College of Cardiology.
    • 07 Jan 2020 Planned End Date changed from 8 May 2019 to 30 Nov 2020.
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