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A Phase 1b Study of Safety and Immune Response to PVX-410 Vaccine Alone and in Combination With Pembrolizumab in HLA-A2+ Patients With Metastatic Triple Negative Breast Cancer (TNBC)

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Trial Profile

A Phase 1b Study of Safety and Immune Response to PVX-410 Vaccine Alone and in Combination With Pembrolizumab in HLA-A2+ Patients With Metastatic Triple Negative Breast Cancer (TNBC)

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 21 Nov 2023

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At a glance

  • Drugs Pembrolizumab (Primary) ; PVX 410 (Primary) ; Poly ICLC
  • Indications Advanced breast cancer; Triple negative breast cancer
  • Focus Pharmacodynamics
  • Most Recent Events

    • 13 Nov 2023 Planned End Date changed from 31 Dec 2024 to 31 Dec 2025.
    • 13 Nov 2023 Planned primary completion date changed from 30 Jun 2023 to 30 Jun 2024.
    • 21 Dec 2022 Planned primary completion date changed from 31 Dec 2022 to 30 Jun 2023.

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