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A Randomized, Single-center, Placebo and Positive Control, 4-period and 4-crossover Clinical Study Evaluating the Effect of a Single-dose Oral Administration of Nemonoxacin Malate Capsule on QTc Intervals and Heart Rhythms of Healthy Subjects as Well as the Influence of Food Intake on QTc Intervals and Pharmacokinetic Characteristics

Trial Profile

A Randomized, Single-center, Placebo and Positive Control, 4-period and 4-crossover Clinical Study Evaluating the Effect of a Single-dose Oral Administration of Nemonoxacin Malate Capsule on QTc Intervals and Heart Rhythms of Healthy Subjects as Well as the Influence of Food Intake on QTc Intervals and Pharmacokinetic Characteristics

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Jan 2020

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At a glance

  • Drugs Nemonoxacin (Primary) ; Moxifloxacin
  • Indications Community-acquired pneumonia; Diabetic foot ulcer; Skin and soft tissue infections
  • Focus Pharmacokinetics
  • Sponsors TaiGen Biotechnology
  • Most Recent Events

    • 23 May 2018 Results (n=48) assessing the effects of nemonoxacin on ECG-measured QT/QTc interval in the fasted and fed conditions and find relationships between QT/QTc and drug absorption, were published in the Clinical Therapeutics.
    • 08 Dec 2017 New trial record
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