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A Phase 1b/2 Study of CPI-1205, a Small Molecule Inhibitor of EZH2, Combined With Enzalutamide or Abiraterone/Prednisone in Patients With Metastatic Castration Resistant Prostate Cancer

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Trial Profile

A Phase 1b/2 Study of CPI-1205, a Small Molecule Inhibitor of EZH2, Combined With Enzalutamide or Abiraterone/Prednisone in Patients With Metastatic Castration Resistant Prostate Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 05 Jul 2023

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At a glance

  • Drugs Abiraterone acetate (Primary) ; Enzalutamide (Primary) ; Lirametostat (Primary) ; Prednisone (Primary)
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Acronyms PROSTAR
  • Sponsors Constellation Pharmaceuticals

    • Most Recent Events

    • 23 Jul 2021 Planned End Date changed from 1 May 2021 to 1 Dec 2021.
    • 23 Jul 2021 Planned primary completion date changed from 1 May 2021 to 1 Dec 2021.
    • 08 Jan 2021 Planned End Date changed from 1 Dec 2020 to 1 May 2021.

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