Trial Profile

A Phase 1b/2 Study of the PARP Inhibitor Niraparib in Combination With Trastuzumab in Patients With Metastatic HER2+ Breast Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 03 Feb 2026

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At a glance

Drugs Niraparib (Primary) ; Trastuzumab (Primary)
Indications Advanced breast cancer; HER2 positive breast cancer
Focus Adverse reactions; Therapeutic Use

Most Recent Events

23 Jan 2026 Planned End Date changed from 30 Dec 2026 to 30 Dec 2027.
23 Jan 2026 Planned primary completion date changed from 1 Nov 2026 to 1 Nov 2027.
04 Feb 2025 Planned End Date changed from 30 Dec 2024 to 30 Dec 2026.

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