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A Randomized, Phase 3, Open-label Study of Combinations of REGN2810 (Anti-PD-1 Antibody), Ipilimumab (Anti-CTLA-4 Antibody), and Platinum-based Doublet Chemotherapy in First-line Treatment of Patients With Advanced or Metastatic Non-Small Cell Lung Cancer With Tumors Expressing PD-L1 <50%

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Trial Profile

A Randomized, Phase 3, Open-label Study of Combinations of REGN2810 (Anti-PD-1 Antibody), Ipilimumab (Anti-CTLA-4 Antibody), and Platinum-based Doublet Chemotherapy in First-line Treatment of Patients With Advanced or Metastatic Non-Small Cell Lung Cancer With Tumors Expressing PD-L1 <50%

Recruiting
Phase of Trial: Phase III

Latest Information Update: 24 Nov 2018

At a glance

  • Drugs Cemiplimab (Primary) ; Carboplatin; Cisplatin; Gemcitabine; Ipilimumab; Paclitaxel; Pemetrexed
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms EMPOWER-lung 3
  • Sponsors Regeneron Pharmaceuticals

    • Most Recent Events

    • 26 Sep 2018 Trial design of the study presented at the 19th World Conference on Lung Cancer.
    • 09 Jun 2018 Planned End Date changed from 7 May 2022 to 18 Jul 2022.
    • 09 Jun 2018 Planned primary completion date changed from 7 May 2022 to 18 Jul 2022.
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