An Open-label, Single-arm, Phase 1b Study to Evaluate the Safety and Efficacy of Grapiprant (ARY-007) in Combination With Pembolizumab in Patients With Advanced or Progressive Microsatellite Stable (MSS) Colorectal Cancer (CRC)
Latest Information Update: 26 Oct 2023
Price :
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At a glance
- Drugs Grapiprant (Primary) ; Pembrolizumab (Primary)
- Indications Colorectal cancer
- Focus Adverse reactions
- Sponsors Arrys Therapeutics; Ikena Oncology
- 23 Oct 2023 Status changed from active, no longer recruiting to completed.
- 28 Nov 2022 According to an Ikena Oncology media release, Following a portfolio review, discontinuing the internal clinical development of the EP4 antagonist IK-007 and exploring strategic alternatives for this program Clinical data from IK-007 in microsatellite stable colorectal cancer (MSS-CRC) will be presented in a poster at 2022 European Society for Medical Oncology Immuno-Oncology Congress
- 21 Apr 2022 Planned End Date changed from 1 Mar 2022 to 1 Sep 2022.