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A Phase Ib Study of Ruxolitinib in Combination With PU-H71 for the Treatment of Subjects With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV MF), and Post-EssentialThrombocythemia MF (Post-ET MF)

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A Phase Ib Study of Ruxolitinib in Combination With PU-H71 for the Treatment of Subjects With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV MF), and Post-EssentialThrombocythemia MF (Post-ET MF)

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Zelavespib (Primary) ; Ruxolitinib
  • Indications Essential thrombocythaemia; Myelofibrosis; Polycythaemia vera
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Samus Therapeutics

    • Most Recent Events

    • 19 Oct 2020 Status changed from active, no longer recruiting to discontinued.
    • 17 Mar 2020 Planned End Date changed from 1 Dec 2019 to 1 Dec 2020.
    • 17 Mar 2020 Planned primary completion date changed from 1 Oct 2019 to 1 Oct 2020.

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