Trial Profile

A Multiarm, Open-label, Multicenter, Phase 1b/2 Study to Evaluate Novel Combination Therapies in Subjects With Previously Treated Advanced EGFRm NSCLC

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 16 Jul 2026

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At a glance

Drugs Imaradenant (Primary) ; Oleclumab (Primary) ; Osimertinib (Primary)
Indications Non-small cell lung cancer
Focus Adverse reactions; Therapeutic Use
Sponsors AstraZeneca; MedImmune

Most Recent Events

13 Jul 2026 Planned End Date changed from 16 Apr 2026 to 6 Nov 2026.
10 Jun 2025 Planned End Date changed from 16 Mar 2026 to 16 Apr 2026.
05 Mar 2025 Planned End Date changed from 15 Jul 2025 to 16 Mar 2026.

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