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Phase 2 Randomized, Multicenter, Safety and Efficacy Trial to Evaluate Different Oral Benznidazole Monotherapy and Benznidazole/E1224 Combination Regimens for the Treatment of Adult Patients With Chronic Indeterminate Chagas Disease

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Phase 2 Randomized, Multicenter, Safety and Efficacy Trial to Evaluate Different Oral Benznidazole Monotherapy and Benznidazole/E1224 Combination Regimens for the Treatment of Adult Patients With Chronic Indeterminate Chagas Disease

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Benznidazole (Primary) ; Fosravuconazole (Primary)
  • Indications Chagas disease
  • Focus Proof of concept; Therapeutic Use
  • Acronyms BENDITA

    • Most Recent Events

    • 01 Aug 2021 Status changed from active, no longer recruiting to completed, as per Results published in The Lancet Infectious Diseases
    • 01 Aug 2021 Primary endpoint has been met. (Parasitological response as determined by serial negative qualitative PCR results (3 negative PCR results, from 3 samples to be collected in the same day) at EOT and sustained parasitological clearance until 6 months follow-up.), as per Results published in The Lancet Infectious Diseases
    • 01 Aug 2021 Results published in The Lancet Infectious Diseases

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