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A Phase I/II Trial to Evaluate the Safety and Tolerability of Clazakizumab (Anti-IL-6 Monoclonal) to Eliminate Donor Specific HLA Antibodies (DSAs) and Improve Transplant Rates in Highly-HLA Sensitized Patients Awaiting Renal Transplant

Trial Profile

A Phase I/II Trial to Evaluate the Safety and Tolerability of Clazakizumab (Anti-IL-6 Monoclonal) to Eliminate Donor Specific HLA Antibodies (DSAs) and Improve Transplant Rates in Highly-HLA Sensitized Patients Awaiting Renal Transplant

Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 16 May 2018

At a glance

  • Drugs Clazakizumab (Primary)
  • Indications Renal transplant rejection
  • Focus Adverse reactions; Pharmacodynamics
  • Most Recent Events

    • 31 Aug 2018 Biomarkers information updated
    • 21 Feb 2018 Status changed from not yet recruiting to recruiting.
    • 18 Jan 2018 Planned initiation date changed from 1 Jan 2018 to 1 Feb 2018.
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