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A Multi-centre, Phase I, Open-label, Single-dose Study to Investigate Pharmacokinetics (PK) of Ticagrelor in Infants and Toddlers, Aged 0 to Less Than 24 Months, With Sickle Cell Disease (HESTIA4)

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Trial Profile

A Multi-centre, Phase I, Open-label, Single-dose Study to Investigate Pharmacokinetics (PK) of Ticagrelor in Infants and Toddlers, Aged 0 to Less Than 24 Months, With Sickle Cell Disease (HESTIA4)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 22 Jul 2022

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At a glance

  • Drugs Ticagrelor (Primary)
  • Indications Sickle cell anaemia
  • Focus Pharmacokinetics
  • Acronyms HESTIA4
  • Sponsors AstraZeneca AB

    • Most Recent Events

    • 06 Nov 2019 Results of HESTIA4 study assessing whether ticagrelor exposure in children less than 24 months old is similar to that in older children and for further dose selection, final PK data from children 2 to <18 years were used from HESTIA1 study, released in 61st Annual Meeting and Exposition of the American Society of Hematology
    • 07 Jun 2019 Status changed from recruiting to completed.
    • 02 Jan 2018 New trial record

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