A study evaluating the effect of new formulation, food or a proton pump inhibitor on the relative bioavailability of the Glasdegib in healthy volunteers.
Latest Information Update: 02 Jan 2018
At a glance
- Drugs Glasdegib (Primary) ; Rabeprazole (Primary) ; Glasdegib
- Indications Acute myeloid leukaemia; Cancer; Chronic myeloid leukaemia; Chronic myelomonocytic leukaemia; Colorectal cancer; Graft-versus-host disease; Haematological malignancies; Myelodysplastic syndromes; Myelofibrosis; Non-small cell lung cancer
- Focus Pharmacokinetics
- Sponsors Pfizer
- 02 Jan 2018 New trial record
- 01 Dec 2017 Primary endpoint (Bioavailability of Formulation A and Formulation B relative to the current diHCl-based reference formulation.) has been met as per the results published in the Cancer Chemotherapy and Pharmacology
- 01 Dec 2017 Results published in the Cancer Chemotherapy and Pharmacology