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CMV-MVA Triplex Vaccine to Enhance Adaptive NK Cell Reconstitution After Autologous Hematopoietic Cell Transplantation in Patients With Lymphoid Malignancies

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Trial Profile

CMV-MVA Triplex Vaccine to Enhance Adaptive NK Cell Reconstitution After Autologous Hematopoietic Cell Transplantation in Patients With Lymphoid Malignancies

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 28 Jun 2022

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At a glance

  • Drugs MVA CMV (Primary)
  • Indications Cytomegalovirus infections
  • Focus Pharmacodynamics

    • Most Recent Events

    • 01 Jun 2022 Primary endpoint has been met. (Change in the absolute number of CMV-induced adaptive NK cells (CD56dimCD57+NKG2C+) between days 28 and 100 post-auto-HCT in patients with lymphoid malignancies.), as per Results published in the Transplantation and Cellular Therapy
    • 01 Jun 2022 Results published in the Transplantation and Cellular Therapy
    • 31 Dec 2019 Status changed from active, no longer recruiting to completed.
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