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Phase II Randomized Trial of Radiotherapy With Concurrent and Adjuvant Pembrolizumab (Keytruda®) Versus Concurrent Chemotherapy in Patients With Advanced/Intermediate-Risk p16+ Head and Neck Squamous Cell Carcinoma (KEYCHAIN)

Trial Profile

Phase II Randomized Trial of Radiotherapy With Concurrent and Adjuvant Pembrolizumab (Keytruda®) Versus Concurrent Chemotherapy in Patients With Advanced/Intermediate-Risk p16+ Head and Neck Squamous Cell Carcinoma (KEYCHAIN)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 08 Aug 2024

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At a glance

  • Drugs Pembrolizumab (Primary) ; Cisplatin
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Nasopharyngeal cancer; Oropharyngeal cancer; Pharyngeal disorders; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms KEYCHAIN

Most Recent Events

  • 06 Aug 2024 Planned End Date changed from 1 Jun 2025 to 31 Dec 2026.
  • 06 Aug 2024 Planned primary completion date changed from 1 Aug 2024 to 31 Dec 2025.
  • 01 May 2023 Planned End Date changed from 1 Jun 2024 to 1 Jun 2025.

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