TLD-1, a Novel Liposomal Doxorubicin, in Patients With Advanced Solid Tumors: A Multicenter Open-label Single-arm Phase I Trial
Latest Information Update: 04 Dec 2024
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At a glance
- Drugs Doxorubicin liposomal (Primary) ; Doxorubicin liposomal
- Indications Advanced breast cancer; Carcinoma; Cervical cancer; Cholangiocarcinoma; Colon cancer; Fallopian tube cancer; Mesothelioma; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Sarcoma; Solid tumours; Uterine cancer
- Focus Adverse reactions; First in man; Pharmacokinetics
- 02 Dec 2024 Status changed from recruiting to discontinued. ( The premature termination is based on the unexpectedly low patient accrual to the clinical trial and the strategic considerations in the development of the TLD-1 after having included 13 out of 14 patients in the comparative PK part.)
- 21 Nov 2023 Planned End Date changed from 1 Oct 2023 to 1 Oct 2024.
- 21 Nov 2023 Planned primary completion date changed from 1 Oct 2023 to 1 Oct 2024.