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A Phase 1, Open-label, Fixed-sequence Study to Evaluate the Effect of UGT Inhibition by Valproic Acid on the Pharmacokinetics of BIIB074 in Healthy Subjects

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Trial Profile

A Phase 1, Open-label, Fixed-sequence Study to Evaluate the Effect of UGT Inhibition by Valproic Acid on the Pharmacokinetics of BIIB074 in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Sep 2022

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At a glance

  • Drugs Vixotrigine (Primary) ; Valproic acid
  • Indications Erythromelalgia; Neuropathic pain; Trigeminal neuralgia
  • Focus Pharmacokinetics
  • Sponsors Biogen

    • Most Recent Events

    • 31 Aug 2022 Results evaluating the effects of a uridine diphosphate-glucuronosyltransferase inhibitor, valproic acid, on vixotrigine pharmacokinetics, published in the Clinical Drug Investigation
    • 04 Jan 2018 New trial record

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