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A Phase Ia/Ib, Open-Label, Dose-Escalation, and Dose-Expansion Study of the Anti-CTLA-4 Monoclonal Antibody CS1002 as Monotherapy and in Combination With Anti-PD-1 Monoclonal Antibody CS1003 in Subjects With Advanced Solid Tumors

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Trial Profile

A Phase Ia/Ib, Open-Label, Dose-Escalation, and Dose-Expansion Study of the Anti-CTLA-4 Monoclonal Antibody CS1002 as Monotherapy and in Combination With Anti-PD-1 Monoclonal Antibody CS1003 in Subjects With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 19 Dec 2022

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At a glance

  • Drugs Ipilimumab (Primary) ; Nofazinlimab (Primary)
  • Indications Adenocarcinoma; Cholangiocarcinoma; Colorectal cancer; Endometrial cancer; Liver cancer; Malignant melanoma; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors CStone Pharmaceuticals
  • Most Recent Events

    • 15 Dec 2022 Status changed from active, no longer recruiting to completed.
    • 09 Aug 2022 Planned End Date changed from 1 Jan 2022 to 7 Jun 2023.
    • 09 Aug 2022 Planned primary completion date changed from 31 Dec 2021 to 7 Jun 2023.

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