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Randomized Phase III Trial of Local Consolidation Therapy (LCT) After Nivolumab and Ipilimumab for Immunotherapy-Naive Patients With Metastatic Non-Small Cell Lung Cancer (LONESTAR)

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Trial Profile

Randomized Phase III Trial of Local Consolidation Therapy (LCT) After Nivolumab and Ipilimumab for Immunotherapy-Naive Patients With Metastatic Non-Small Cell Lung Cancer (LONESTAR)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 13 Jan 2026

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At a glance

  • Drugs Ipilimumab (Primary) ; Nivolumab (Primary)
  • Indications Adenocarcinoma; Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms LONESTAR

Most Recent Events

  • 17 Dec 2025 Planned End Date changed from 31 Dec 2025 to 31 Mar 2026.
  • 17 Dec 2025 Planned primary completion date changed from 31 Dec 2025 to 31 Mar 2026.
  • 10 Nov 2025 Status changed from recruiting to active, no longer recruiting.

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