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A Phase I/II Trial to Evaluate the Safety and Immunogenicity of a Messenger RNA (mRNA)-Based, Personalized Cancer Vaccine Against Neoantigens Expressed by the Autologous Cancer

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Trial Profile

A Phase I/II Trial to Evaluate the Safety and Immunogenicity of a Messenger RNA (mRNA)-Based, Personalized Cancer Vaccine Against Neoantigens Expressed by the Autologous Cancer

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs NCI-4650 (Primary)
  • Indications Adenocarcinoma; Carcinoma; Colon cancer; Gastric cancer; Gastrointestinal cancer; Malignant melanoma; Rectal cancer; Urogenital cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 08 Nov 2019 Status changed from completed to discontinued.
    • 06 Nov 2019 According to a Moderna Therapeutics media release, data from this study has been submitted for the publication.
    • 26 Jun 2019 Status changed from recruiting to completed.

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