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A Single-Arm, Multicenter, Phase 2 Study of Brigatinib in Japanese Patients With ALK-Positive Non-Small Cell Lung Cancer (NSCLC)

Trial Profile

A Single-Arm, Multicenter, Phase 2 Study of Brigatinib in Japanese Patients With ALK-Positive Non-Small Cell Lung Cancer (NSCLC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Sep 2023

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At a glance

  • Drugs Brigatinib (Primary)
  • Indications Adenocarcinoma; Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms J-ALTA
  • Sponsors Takeda
  • Most Recent Events

    • 01 Sep 2023 Results of Exploratory analysis assessing the efficacy and safety of brigatinib in Japanese patients with advanced ALK+ non-small-cell lung cancer published in the Cancer Science
    • 06 Jun 2023 Results of pooled analysis from ALTA-1L and J-ALTA , presented at the 59th Annual Meeting of the American Society of Clinical Oncology
    • 13 Sep 2022 Results of pooled analysis from NCT03535740 and NCT03410108 of exploratory integrated analysis of the impact of EML4-ALK fusion and secondary ALK mutations on efficacy with brigatinib in alectinib-refractory ALK+ NSCLC patients, presented at the 47th European Society for Medical Oncology Congress
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