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A Randomized, Double-blind, Multicenter Study to Assess the Efficacy and Safety of a 6 Month Oral Treatment With the Chymase Inhibitor BAY 1142524 at a Dose of 25 mg BID in Comparison to Placebo on Top of Standard of Care in Patients With Type II Diabetes and a Clinical Diagnosis of Diabetic Kidney Disease

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A Randomized, Double-blind, Multicenter Study to Assess the Efficacy and Safety of a 6 Month Oral Treatment With the Chymase Inhibitor BAY 1142524 at a Dose of 25 mg BID in Comparison to Placebo on Top of Standard of Care in Patients With Type II Diabetes and a Clinical Diagnosis of Diabetic Kidney Disease

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 04 Mar 2022

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At a glance

  • Drugs Fulacimstat (Primary)
  • Indications Diabetic nephropathies
  • Focus Biomarker; Therapeutic Use
  • Acronyms CADA DIA
  • Sponsors Bayer

    • Most Recent Events

    • 26 Dec 2020 Primary endpoint (Change in urinary albumin to creatinine ratio (UACR)) has not been met according to Results published in the Nephrology Dialysis Transplantation.
    • 26 Dec 2020 Results published in the Nephrology Dialysis Transplantation
    • 30 Oct 2019 Status changed from active, no longer recruiting to completed.

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