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An Open Label Single Arm Phase I/II Study of MTX110 Delivered by Convection-enhanced Delivery (CED) in Patients With Diffuse Intrinsic Pontine Glioma (DIPG) Previously Treated With External Beam Radiation Therapy

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Trial Profile

An Open Label Single Arm Phase I/II Study of MTX110 Delivered by Convection-enhanced Delivery (CED) in Patients With Diffuse Intrinsic Pontine Glioma (DIPG) Previously Treated With External Beam Radiation Therapy

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 23 Nov 2023

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At a glance

  • Drugs Panobinostat (Primary) ; Gadoteridol
  • Indications Diffuse intrinsic pontine glioma; Glioma
  • Focus Adverse reactions; First in man

    • Most Recent Events

    • 02 Nov 2023 Results published in the Neuro-Oncology.
    • 06 Jul 2023 According to a Biodexa Pharmaceuticals Media Release, the company has announced the publication of the results of an investigator-initiated Phase I study PNOC015 (also known as MTD-201) of MTX110 in the treatment of pediatric patients with DMG (formerly known as Diffuse Intrinsic Pontine Glioma, or DIPG) in the Journal of Neuro-Oncology.
    • 08 Apr 2021 Status changed from active, no longer recruiting to completed.
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