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A Phase 1 Study of CPI-1205 With Ipilimumab in Patients With Advanced Solid Tumors Followed by a Phase 2 Basket Study of CPI-1205 With Ipilimumab in Selected Tumor Types Previously Treated With PD-1 or PD-L1 Inhibitors

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Trial Profile

A Phase 1 Study of CPI-1205 With Ipilimumab in Patients With Advanced Solid Tumors Followed by a Phase 2 Basket Study of CPI-1205 With Ipilimumab in Selected Tumor Types Previously Treated With PD-1 or PD-L1 Inhibitors

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 19 May 2022

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At a glance

  • Drugs Lirametostat (Primary) ; Ipilimumab
  • Indications Bladder cancer; Malignant melanoma; Non-small cell lung cancer; Pelvic cancer; Renal cancer; Renal cell carcinoma; Solid tumours; Ureteral neoplasms; Urethral cancer; Urogenital cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ORIOn-E
  • Sponsors Constellation Pharmaceuticals
  • Most Recent Events

    • 07 Jan 2021 Status changed from active, no longer recruiting to completed.
    • 04 Jan 2019 Planned End Date changed from 1 Jun 2020 to 1 Dec 2019.
    • 04 Jan 2019 Planned primary completion date changed from 1 Jun 2020 to 1 Dec 2019.

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