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PARPVAX: Parpvax: A Phase 1b/2, Open Label Study of Niraparib Plus Either Ipilimumab or Nivolumab in Patients With Advanced Pancreatic Cancer Whose Disease Has Not Progressed on Platinum-based Therapy

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Trial Profile

PARPVAX: Parpvax: A Phase 1b/2, Open Label Study of Niraparib Plus Either Ipilimumab or Nivolumab in Patients With Advanced Pancreatic Cancer Whose Disease Has Not Progressed on Platinum-based Therapy

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 04 Dec 2024

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At a glance

  • Drugs Ipilimumab (Primary) ; Niraparib (Primary) ; Nivolumab (Primary)
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms Parpvax

    • Most Recent Events

    • 02 Dec 2024 Status changed from active, no longer recruiting to completed.
    • 07 Jul 2022 Primary endpoint (Progression-free survival) for niraparib plus ipilimumab maintenance group has been met, as per Results published in the Lancet Oncology
    • 07 Jul 2022 Results published in the Lancet Oncology

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