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A Phase 1/2 Dose Escalation and Dose Expansion Study of Mecbotamab Vedotin (BA3011) Alone and in Combination with Nivolumab in Adult and Adolescent Patients 12 Years and Older with Advanced Solid Tumors

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Trial Profile

A Phase 1/2 Dose Escalation and Dose Expansion Study of Mecbotamab Vedotin (BA3011) Alone and in Combination with Nivolumab in Adult and Adolescent Patients 12 Years and Older with Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 28 Jun 2026

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At a glance

  • Drugs Mecbotamab vedotin (Primary) ; Nivolumab (Primary)
  • Indications Adenocarcinoma; Bone cancer; Leiomyosarcoma; Liposarcoma; Malignant fibrous histiocytoma; Malignant melanoma; Non-small cell lung cancer; Pancreatic cancer; Prostate cancer; Sarcoma; Soft tissue sarcoma; Solid tumours
  • Focus Adverse reactions; First in man; Registrational; Therapeutic Use
  • Sponsors BioAtla

Most Recent Events

  • 02 Jun 2026 Results presented at the 62nd Annual Meeting of the American Society of Clinical Oncology
  • 07 Nov 2025 According to a Bioatla media release, data from the trial were presented at the Society for Immunotherapy of Cancer (SITC) 2025 Annual Meeting, being held November 5-9, 2025, in National Harbor, Maryland.
  • 07 Nov 2025 Results presented in the BioAtla Media Release

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