Trial Profile

A Phase 1/2 Dose Escalation and Dose Expansion Study of Mecbotamab Vedotin (BA3011) Alone and in Combination with Nivolumab in Adult and Adolescent Patients 12 Years and Older with Advanced Solid Tumors

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 10 Oct 2025

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At a glance

Drugs Mecbotamab vedotin (Primary) ; Nivolumab (Primary)
Indications Adenocarcinoma; Bone cancer; Malignant fibrous histiocytoma; Malignant melanoma; Non-small cell lung cancer; Pancreatic cancer; Prostate cancer; Sarcoma; Soft tissue sarcoma; Solid tumours
Focus Adverse reactions; First in man; Registrational; Therapeutic Use
Sponsors BioAtla

23 Sep 2025 Actual primary completion date changed from 30 Jan 2025 to 8 Jan 2025.
23 Sep 2025 Status changed from active, no longer recruiting to completed.
15 Jun 2025 Planned End Date changed from 1 Jan 2025 to 30 Jun 2025.

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