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A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

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Trial Profile

A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 18 Oct 2023

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At a glance

  • Drugs Napabucasin (Primary) ; Bupropion; Caffeine; Dextromethorphan; Flurbiprofen; Midazolam; Midazolam; Omeprazole; Repaglinide; Rosuvastatin
  • Indications Colorectal cancer; Gastrointestinal cancer; Glioblastoma; Liver cancer; Malignant melanoma; Non-small cell lung cancer; Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Boston Biomedical; Sumitomo Pharma Oncology

    • Most Recent Events

    • 25 Jan 2020 Results (N=17), analysis of drug-drug interaction potential of Napabucasin, presented at the 2020 Gastrointestinal Cancers Symposium
    • 03 Apr 2018 Status changed from recruiting to completed.
    • 29 Jan 2018 New trial record

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