HEXT: The Hypoparathyroidism Studies, EXTended: The Effect of PTH on the Skeleton in Hypoparathyroidism
Latest Information Update: 17 Jul 2024
At a glance
- Drugs Parathyroid hormone (Primary)
- Indications Hypoparathyroidism
- Focus Therapeutic Use
- Acronyms HEXT
- 05 Jul 2024 Status changed from active, no longer recruiting to completed.
- 26 Aug 2022 Results (n=248) assessing the changes in estimated glomerular filtration rate over a 5-year period in adult patients with chronic hypoparathyroidism treated with recombinant parathyroid hormone (1-84), rhPTH(1-84), compared with a historical control cohort of patients who did not receive rhPTH(1-84) from REPLACE (NCT00732615), RELAY (NCT01268098), RACE (NCT01297309), and HEXT (NCT01199614 and continuation study NCT02910466) studies, published in the Advances in Therapy.
- 23 Mar 2021 Results of comparative analysis with a historical control cohort with patients data pooled from NCT00732615 (REPLACE), NCT01268098 (RELAY), NCT01297309 (RACE) and NCT01199614 (HEXT) clinical trials assessing the chronic kidney disease (CKD) outcomes over a period of up to 5 years in adult patients with chronic hypoparathyroidism treated with recombinant human parathyroid hormone presented at the 103rd Annual Meeting of the Endocrine Society