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HEXT: The Hypoparathyroidism Studies, EXTended: The Effect of PTH on the Skeleton in Hypoparathyroidism

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Trial Profile

HEXT: The Hypoparathyroidism Studies, EXTended: The Effect of PTH on the Skeleton in Hypoparathyroidism

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 30 Aug 2022

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At a glance

  • Drugs Parathyroid hormone (Primary)
  • Indications Hypoparathyroidism
  • Focus Therapeutic Use
  • Acronyms HEXT
  • Most Recent Events

    • 26 Aug 2022 Results (n=248) assessing the changes in estimated glomerular filtration rate over a 5-year period in adult patients with chronic hypoparathyroidism treated with recombinant parathyroid hormone (1-84), rhPTH(1-84), compared with a historical control cohort of patients who did not receive rhPTH(1-84) from REPLACE (NCT00732615), RELAY (NCT01268098), RACE (NCT01297309), and HEXT (NCT01199614 and continuation study NCT02910466) studies, published in the Advances in Therapy.
    • 23 Mar 2021 Results of comparative analysis with a historical control cohort with patients data pooled from NCT00732615 (REPLACE), NCT01268098 (RELAY), NCT01297309 (RACE) and NCT01199614 (HEXT) clinical trials assessing the chronic kidney disease (CKD) outcomes over a period of up to 5 years in adult patients with chronic hypoparathyroidism treated with recombinant human parathyroid hormone presented at the 103rd Annual Meeting of the Endocrine Society
    • 23 Mar 2021 Results of comparative analysis with a historical control cohort with patients data pooled from NCT01297309 (RACE) and NCT01199614 (HEXT) clinical trials assessing the Change in estimated glomerular filtration rate in adult patients with chronic Hypoparathyroidism treated with rhPTH, presented at the 103rd Annual Meeting of the Endocrine Society
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