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Prospective Phase I/II Trial to Jointly Optimize the Administration Schedule(s) and Dose(s) of Melphalan for Injection (Evomela) as a Preparative Regimen for Autologous Hematopoietic Stem Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma

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Prospective Phase I/II Trial to Jointly Optimize the Administration Schedule(s) and Dose(s) of Melphalan for Injection (Evomela) as a Preparative Regimen for Autologous Hematopoietic Stem Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 26 Jul 2024

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At a glance

  • Drugs Melphalan (Primary) ; Filgrastim; Palifermin
  • Indications Multiple myeloma
  • Focus Adverse reactions; Pharmacokinetics

    • Most Recent Events

    • 23 Jul 2024 Status changed from active, no longer recruiting to completed.
    • 12 Dec 2023 Results assessing the dose escalation and compared the short versus extended infusion time of evomela used as a conditioning regimen before auto-HCT, were presented at the 65th American Society of Hematology Annual Meeting and Exposition.
    • 26 Oct 2023 Planned End Date changed from 31 Dec 2023 to 31 Dec 2024.

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