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A Phase II Study of Atezolizumab in Combination With Pertuzumab Plus High-dose Trastuzumab for the Treatment of Central Nervous System Metastases in Patients With Her2-positive Breast Cancer

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Trial Profile

A Phase II Study of Atezolizumab in Combination With Pertuzumab Plus High-dose Trastuzumab for the Treatment of Central Nervous System Metastases in Patients With Her2-positive Breast Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 Aug 2026

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At a glance

  • Drugs Atezolizumab (Primary) ; Pertuzumab (Primary) ; Trastuzumab (Primary)
  • Indications Advanced breast cancer; Brain metastases; HER2 positive breast cancer; Male breast cancer
  • Focus Therapeutic Use

Most Recent Events

  • 21 Aug 2026 Status changed from active, no longer recruiting to completed.
  • 27 Apr 2026 Planned End Date changed from 1 Dec 2025 to 1 May 2026.
  • 12 Jun 2023 Planned primary completion date changed from 1 Jul 2023 to 1 Aug 2024.

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