Trial Profile

A Phase 1/2/3 Study to Evaluate the Safety and Efficacy of a Single Dose of Autologous CRISPR-Cas9 Modified CD34+ Human Hematopoietic Stem and Progenitor Cells (CTX001) in Subjects With Severe Sickle Cell Disease

Status: Completed

Phase of Trial: Phase II/III

Latest Information Update: 07 Sep 2025

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At a glance

11 Aug 2025 Status changed from active, no longer recruiting to completed.
31 Oct 2024 Planned End Date changed from 1 Oct 2024 to 1 Jul 2025.
31 Oct 2024 Planned primary completion date changed from 1 Oct 2024 to 1 Jul 2025.

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