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A Phase 1b-2 Study of the ROR1-Targeting Monoclonal Antibody, Cirmtuzumab, and the Bruton Tyrosine Kinase Inhibitor, Ibrutinib, in Patients With B-Cell Lymphoid Malignancies

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Trial Profile

A Phase 1b-2 Study of the ROR1-Targeting Monoclonal Antibody, Cirmtuzumab, and the Bruton Tyrosine Kinase Inhibitor, Ibrutinib, in Patients With B-Cell Lymphoid Malignancies

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 13 Jan 2023

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At a glance

  • Drugs Ibrutinib (Primary) ; Zilovertamab (Primary)
  • Indications Chronic lymphocytic leukaemia; Mantle-cell lymphoma; Marginal zone B-cell lymphoma
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms CIRLL
  • Sponsors Oncternal Therapeutics, Inc.
  • Most Recent Events

    • 13 Dec 2022 Results (n=95), presented at the 64th American Society of Hematology Annual Meeting and Exposition
    • 10 Dec 2022 According to an Oncternal Therapeutics media release, interim results presented at the American Society of Hematology (ASH) 2022 Annual Meeting.
    • 10 Dec 2022 Interim results (n=33) presented in an Oncternal Therapeutics Media Release.

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