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A Randomized Study Comparing the Efficacy of the Combination of Doxorubicin and the Tumor-targeting Human Antibody-cytokine Fusion Protein L19TNF to Doxorubicin Alone as First-line Therapy in Patients With Metastatic Leiomyosarcoma

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Trial Profile

A Randomized Study Comparing the Efficacy of the Combination of Doxorubicin and the Tumor-targeting Human Antibody-cytokine Fusion Protein L19TNF to Doxorubicin Alone as First-line Therapy in Patients With Metastatic Leiomyosarcoma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 10 Nov 2023

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At a glance

  • Drugs Onfekafusp alfa (Primary) ; Doxorubicin
  • Indications Leiomyosarcoma
  • Focus Therapeutic Use
  • Acronyms FIBROSARC US; FIBROSARC USA
  • Sponsors Philogen

    • Most Recent Events

    • 07 Nov 2023 According to a Philogen media release, this trial is underway at 9 clinical centers in the United States.
    • 07 Apr 2022 Inclusion criteria has been updated to removed the following cancers- histiocytoma, liposarcoma, Fibrosarcoma and Angiosarcoma. thus the focus of the study is only on stage 4 high-grade leiomyosarcoma. Upper age limit is extended from 75 to 100 years.
    • 07 Apr 2022 Planned End Date changed from 1 Sep 2022 to 1 Dec 2025.

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