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A Phase 1, Open-Label, Dose-Finding Study of INCB050465 in Combination With Investigator Choice of Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)

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Trial Profile

A Phase 1, Open-Label, Dose-Finding Study of INCB050465 in Combination With Investigator Choice of Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 13 Jan 2023

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At a glance

  • Drugs Parsaclisib (Primary) ; Bendamustine; Ibrutinib; Rituximab
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma
  • Focus Adverse reactions
  • Acronyms CITADEL-112
  • Sponsors Incyte Corporation
  • Most Recent Events

    • 13 Dec 2022 Results (At data cutoff January 14, 2022) assessing the safety and initial efficacy of parsaclisib in combination with rituximab, bendamustine plus rituximab, or Ibrutinib in patients with previously treated B-cell lymphoma, presented at the 64th American Society of Hematology Annual Meeting and Exposition.
    • 27 Jun 2022 Status changed from active, no longer recruiting to completed.
    • 17 Jun 2022 Results (Cut off - May 14, 2021, N=50) presented at the 27th Congress of the European Haematology Association

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