Trial Profile

A Randomized, Open-label Phase II/III Efficacy and Safety Study of Atezolizumab in Combination With FLOT Versus FLOT Alone in Patients With Gastric Cancer and Adenocarcinoma of the Oesophago-gastric Junction and High Immune Responsiveness (MO30039/MO43340) - The IKF-DANTE Trial

Status: Active, no longer recruiting

Phase of Trial: Phase II/III

Latest Information Update: 08 Aug 2025

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At a glance

Drugs Atezolizumab (Primary) ; Docetaxel; Fluorouracil; Folinic acid; Oxaliplatin
Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
Focus Biomarker; Therapeutic Use
Acronyms DANTE

25 Jul 2025 Status changed from recruiting to active, no longer recruiting.
14 Nov 2023 Interim Results (n=295) of the phase II proportion, focusing on surgical pathology and safety outcomes on an exploratory basis, published in the Journal of Clinical Oncology
08 Aug 2023 Planned number of patients changed from 559 to 674.

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