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A Phase I, First-in-human, Open-label, Dose-escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Oral TP-0184 Administered Once Weekly for 4 Weeks to Patients With Advanced Solid Tumors

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Trial Profile

A Phase I, First-in-human, Open-label, Dose-escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Oral TP-0184 Administered Once Weekly for 4 Weeks to Patients With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 18 Oct 2023

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At a glance

  • Drugs Itacnosertib (Primary)
  • Indications Colorectal cancer; Lung cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Sumitomo Dainippon Pharma Oncology; Sumitomo Pharma America; Tolero Pharmaceuticals

    • Most Recent Events

    • 13 Apr 2022 Preliminary Results (At data cutoff May 27, 2021) presented at the 113th Annual Meeting of the American Association for Cancer Research
    • 08 Apr 2022 According to a Sumitomo Dainippon Pharma media release, data from this study will be presented at the American Association for Cancer Research (AACR) Annual Meeting
    • 21 Oct 2021 Status changed from active, no longer recruiting to completed.

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