Trial Profile

A Phase I Study of Tovorafenib/DAY101 (Formerly TAK-580, MLN2480) for Children With Low-Grade Gliomas and Other RAS/RAF/MEK/ERK Pathway Activated Tumors

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 23 Feb 2026

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At a glance

Drugs Tovorafenib (Primary)
Indications CNS cancer; Glioma; Neurofibromatoses; Solid tumours
Focus Adverse reactions

Most Recent Events

19 Feb 2026 Status changed from active, no longer recruiting to completed.
03 Feb 2025 Planned End Date changed from 31 Dec 2024 to 31 Dec 2025.
03 Feb 2025 Planned primary completion date changed from 31 Dec 2024 to 31 Dec 2025.

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