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A Phase II Study of Durvalumab in Patients With Mismatch Repair Deficient or POLE Mutated Metastatic Colorectal Cancer

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Trial Profile

A Phase II Study of Durvalumab in Patients With Mismatch Repair Deficient or POLE Mutated Metastatic Colorectal Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Dec 2022

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At a glance

  • Drugs Durvalumab (Primary)
  • Indications Adenocarcinoma; Colon cancer; Rectal cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 15 Dec 2022 Planned End Date changed from 31 May 2022 to 31 Dec 2023.
    • 15 Dec 2022 Planned primary completion date changed from 31 Mar 2022 to 30 Jun 2023.
    • 02 May 2022 Results evaluate the clinical efficacy of durvalumab in patients with microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) or polymerase epsilon mutated metastatic or unresectable colorectal cancer, published in the International Journal of Cancer

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