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A Phase 2, Randomized, Open-Label, Active-Controlled Study to Evaluate the Safety and Antiviral Activity of GS-9992 Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Chronic Hepatitis B (CHB) Subjects

Trial Profile

A Phase 2, Randomized, Open-Label, Active-Controlled Study to Evaluate the Safety and Antiviral Activity of GS-9992 Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Chronic Hepatitis B (CHB) Subjects

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 13 Aug 2021

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At a glance

  • Drugs Inarigivir soproxil (Primary) ; Tenofovir alafenamide (Primary)
  • Indications Hepatitis B
  • Focus Therapeutic Use
  • Sponsors Gilead Sciences
  • Most Recent Events

    • 26 Jun 2021 Results presented at The International Liver Congress 2021
    • 20 Nov 2020 According to a F-star Therapeutics media release, F-star Therapeutics has acquired Spring Bank Pharmaceuticals. The Spring Bank has been re-named to F-star Therapeutics.
    • 29 Jan 2020 According to a Spring Bank Pharmaceuticals media release, the company has discontinued development of inarigivir soproxil, which was in Phase 2 development for the treatment of chronic hepatitis B virus (HBV). This decision was made in the interest of patient safety based on the occurrence of unexpected serious adverse events, including one patient death, in Spring Banks Phase 2b CATALYST trial.
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