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A Phase Ib Investigation of Pembrolizumab in Combination With Intratumoral Injection of Clostridium Novyi-NT in Patients With Treatment-Refractory Solid Tumors

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A Phase Ib Investigation of Pembrolizumab in Combination With Intratumoral Injection of Clostridium Novyi-NT in Patients With Treatment-Refractory Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 24 Apr 2024

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At a glance

  • Drugs Clostridium novyi-NT (Primary) ; Pembrolizumab (Primary) ; Doxycycline
  • Indications Chordoma; Head and neck cancer; Malignant melanoma; Nasopharyngeal cancer; Solid tumours; Squamous cell cancer; Vulval disorders
  • Focus Adverse reactions

    • Most Recent Events

    • 18 Apr 2024 Status changed from recruiting to active, no longer recruiting.
    • 19 Apr 2023 Results(n=16) assessing safety and efficacy of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors presented at the 114th Annual Meeting of the American Association for Cancer Research
    • 18 Apr 2022 Planned End Date changed from 1 Oct 2021 to 1 Oct 2024.

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