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Multicenter Pilot Study of the Safety, Efficacy, and Immune Cell Profiling in Advanced Hepatocellular Carcinoma (HCC) Patients Treated With the Combination of Sorafenib Plus Nivolumab as First-Line of Systemic Therapy

Trial Profile

Multicenter Pilot Study of the Safety, Efficacy, and Immune Cell Profiling in Advanced Hepatocellular Carcinoma (HCC) Patients Treated With the Combination of Sorafenib Plus Nivolumab as First-Line of Systemic Therapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 13 Feb 2025

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At a glance

  • Drugs Nivolumab (Primary) ; Sorafenib (Primary)
  • Indications Liver cancer
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 11 Feb 2025 Study arms increased from 2 to 3. Part 2: Child-Pugh B (CPB) Expansion Cohort (sorafenib, nivolumab) arm added newly to the intervention.
  • 11 Feb 2025 Status changed from active, no longer recruiting to completed.
  • 01 Feb 2023 Planned End Date changed from 31 Dec 2023 to 30 Nov 2024.

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