Trial Profile
A phase 1 study of subcutaneous formulation of ALXN1210 with ENHANZE drug-delivery technology
Status:
Completed
Phase of Trial:
Phase I
Latest Information Update: 30 Jul 2019
Price :
$35
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At a glance
- Drugs Ravulizumab (Primary)
- Indications Haemolytic uraemic syndrome; Immunological disorders; Paroxysmal nocturnal haemoglobinuria
- Focus Adverse reactions
- Sponsors Alexion Pharmaceuticals
- 24 Jul 2019 Status changed from planning to completed according to an Alexion Pharmaceuticals media release.
- 26 Jul 2018 According to an Alexion Pharmaceuticals media release, the company has filed a Clinical Trial Application in the EU for subcutaneous ALXN1210 co-administered with Halozymes ENHANZE drug-delivery technology, PH20, and plans to initiate this phase I study in the second half of 2018.Pending co-formulation data, this next-generation subcutaneous formulation will be called ALXN1810 and has the potential to further extend the dosing interval to once every two weeks or once per month.
- 23 Feb 2018 New trial record