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A Phase I Study of Avelumab Plus Utomilumab-Based Combination Therapy for Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Mantle Cell Lymphoma

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Trial Profile

A Phase I Study of Avelumab Plus Utomilumab-Based Combination Therapy for Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Mantle Cell Lymphoma

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Apr 2025

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At a glance

  • Drugs Avelumab (Primary) ; Ibrutinib (Primary) ; Rituximab (Primary) ; Utomilumab (Primary) ; Carboplatin; Etoposide phosphate; Ifosfamide
  • Indications Diffuse large B cell lymphoma; Mantle-cell lymphoma
  • Focus Adverse reactions

Most Recent Events

  • 26 Mar 2025 Status changed from active, no longer recruiting to completed.
  • 27 Mar 2024 Planned End Date changed from 30 Dec 2023 to 30 Dec 2024.
  • 27 Mar 2024 Planned primary completion date changed from 30 Dec 2023 to 30 Dec 2024.

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