Trial Profile

Daratumumab and Ibrutinib for Symptomatic, Treatment-Naive CLL: A Phase 1b Proof-of-Concept Study

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 10 Oct 2025

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At a glance

Drugs Daratumumab (Primary) ; Ibrutinib (Primary)
Indications Chronic lymphocytic leukaemia
Focus Adverse reactions; Proof of concept; Therapeutic Use

Most Recent Events

24 Sep 2025 Planned End Date changed from 15 Aug 2025 to 15 Apr 2026.
24 Sep 2025 Planned primary completion date changed from 25 Jul 2025 to 1 Dec 2025.
04 Apr 2025 Planned End Date changed from 31 Dec 2024 to 15 Aug 2025.

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