A Phase 1 Multiple-Dose Study to Evaluate the Safety and Tolerability of XmAb®23104 in Subjects With Selected Advanced Solid Tumors
Latest Information Update: 17 Jul 2024
At a glance
- Drugs Ipilimumab (Primary) ; Izuralimab (Primary)
- Indications Advanced breast cancer; Carcinoma; Cervical cancer; Colorectal cancer; Endometrial cancer; Fibroma; Gastric cancer; Head and neck cancer; Liver cancer; Malignant fibrous histiocytoma; Malignant melanoma; Multiple myeloma; Nasopharyngeal cancer; Non-small cell lung cancer; Pancreatic cancer; Renal cell carcinoma; Sarcoma; Small cell lung cancer; Soft tissue sarcoma; Solid tumours; Squamous cell cancer; Urogenital cancer
- Focus Adverse reactions; First in man
- Acronyms DUET-3
- Sponsors Xencor
Most Recent Events
- 05 Jul 2024 Status changed from active, no longer recruiting to completed.
- 08 Feb 2024 Status changed from recruiting to active, no longer recruiting.
- 07 Nov 2023 According to Xencor media release, the company will will stop internal development of XmAb104 due to emerging data from Phase 1 expansion cohorts not meeting efficacy criteria for advancing the program. The Company will continue to support patients currently enrolled and being treated.