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A Phase III Randomised, Double-blind Trial to Evaluate the Effect of 12 Weeks Treatment of Once Daily EMPagliflozin 10 mg Compared With Placebo on ExeRcise Ability and Heart Failure Symptoms, In Patients With Chronic HeArt FaiLure With Preserved Ejection Fraction (HFpEF) (EMPERIAL - Preserved)

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Trial Profile

A Phase III Randomised, Double-blind Trial to Evaluate the Effect of 12 Weeks Treatment of Once Daily EMPagliflozin 10 mg Compared With Placebo on ExeRcise Ability and Heart Failure Symptoms, In Patients With Chronic HeArt FaiLure With Preserved Ejection Fraction (HFpEF) (EMPERIAL - Preserved)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Empagliflozin (Primary)
  • Indications Chronic heart failure
  • Focus Registrational; Therapeutic Use
  • Acronyms EMPERIAL-Preserved
  • Sponsors Boehringer Ingelheim

Most Recent Events

  • 22 Dec 2020 Results assessing effect of empagliflozin on exercise ability and symptoms in heart failure patients with reduced and preserved ejection fraction published in the European Heart Journal
  • 08 Dec 2020 Primary endpoint (The change from baseline to week 12 in exercise capacity as measured by the distance walked in 6 minutes in standardised conditions) has not been met as per results published in the ClinicalTrials.gov Trial Registry
  • 19 Jun 2020 Results presented in a Boehringer Ingelheim Media Release.

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