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An Open-Label, Dose Escalation, Phase 1, First-in-Human Study of TAK-164, an Antibody-Drug Conjugate, in Patients With Advanced Gastrointestinal Cancers Expressing Guanylyl Cyclase C

Trial Profile

An Open-Label, Dose Escalation, Phase 1, First-in-Human Study of TAK-164, an Antibody-Drug Conjugate, in Patients With Advanced Gastrointestinal Cancers Expressing Guanylyl Cyclase C

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 20 Apr 2023

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At a glance

  • Drugs TAK-164 (Primary)
  • Indications Carcinoma; Colon cancer; Colorectal cancer; Gastric cancer; Gastrointestinal cancer; Oesophageal cancer; Pancreatic cancer
  • Focus Adverse reactions; First in man
  • Sponsors Takeda Oncology
  • Most Recent Events

    • 01 Apr 2023 Results assessing the safety and tolerability of TAK-164 in patients with advanced gastrointestinal cancers expressing guanylyl cyclase C, published in the Cancer Chemotherapy and Pharmacology.
    • 08 Jun 2021 Results presented at the 57th Annual Meeting of the American Society of Clinical Oncology
    • 24 Feb 2021 Status changed from completed to discontinued.
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