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Combined Phase I-Phase II Study of Autologous CD8+ T-cells Transiently Expressing a Chimeric Antigen Receptor Directed to B-Cell Maturation Antigen in Patients With Multiple Myeloma

Trial Profile

Combined Phase I-Phase II Study of Autologous CD8+ T-cells Transiently Expressing a Chimeric Antigen Receptor Directed to B-Cell Maturation Antigen in Patients With Multiple Myeloma

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 18 Feb 2025

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At a glance

  • Drugs Descartes 08 (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Multiple myeloma
  • Focus Adverse reactions
  • Sponsors Cartesian Therapeutics

Most Recent Events

  • 05 Nov 2024 According to a Cartesian Therapeutics media release, the company announced that safety and tolerability data from patients treated with Descartes-08 will be featured during a poster presentation at the upcoming 66th American Society of Hematology (ASH) Annual Meeting and Exposition, being held December 7-10, 2024 in San Diego.
  • 28 Jun 2024 According to ClinicalTrials.gov record, Phase 1 enrollment completed. Further clinical development terminated
  • 28 Jun 2024 Status changed from completed to discontinued.

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